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Artificial Intelligence (AI) techniques have effectively and significantly contributed to the detection of many diseases and have proven their effectiveness and success in diagnosing diseases, especially cancer and intractable diseases, and their accurate classification. Among these techniques are artificial neural networks. This book aims to focus on the detection system using artificial intelligence methods Designed to diagnose melanoma, lung cancer, and Covid-19 using digital image processing techniques. The book contains many steps such as pretreatment, segmentation, feature extraction, and detection process,which give acceptable results for the detection problems of these diseases.