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Zyklin A1 und Interaktionspartner des Zyklin A1-CDK2-Komplexes

Language GermanGerman
Book Paperback
Book Zyklin A1 und Interaktionspartner des Zyklin A1-CDK2-Komplexes Tim Sauer
Libristo code: 05196023
Publishers Sudwestdeutscher Verlag Fur Hochschulschriften AG, July 2014
Die akute myeloische Leukämie (AML) ist eine maligne Erkrankung des hämatopoetischen Systems und gek... Full description
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Die akute myeloische Leukämie (AML) ist eine maligne Erkrankung des hämatopoetischen Systems und gekennzeichnet durch das unkontrollierte, klonale Wachstum unreifer hämatopoetischer Vorläuferzellen. Bei einer Vielzahl von AML-Patienten konnte im Knochenmark eine hohe Expression des Zellzyklusregulationsproteins Zyklin A1 nachgewiesen werden. Hieraus resultierte die Vermutung, dass Zyklin A1 an der Entstehung dieser Leukämie-Form maßgeblich beteiligt sein könnte. Um die Funktion von Zyklin A1 genauer charakterisieren zu können, wurden Interaktionspartner des Zyklin A1-Proteins bzw. des Zyklin A1-CDK2-Komplexes identifiziert. Diese wurden im Rahmen dieser Arbeit einer Genexpressionsanalyse sowie funktionellen Charakterisierung unterzogen.

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About the book

Full name Zyklin A1 und Interaktionspartner des Zyklin A1-CDK2-Komplexes
Author Tim Sauer
Language German
Binding Book - Paperback
Date of issue 2014
Number of pages 128
EAN 9783838139074
ISBN 3838139070
Libristo code 05196023
Publishers Sudwestdeutscher Verlag Fur Hochschulschriften AG
Weight 200
Dimensions 152 x 229 x 8

Categories

Medicine & Nursing > Medicine: general issues
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