VALVULAR HEART DISEASE

Valvular Heart Disease: Comprehensive Diagnosis, Advanced Imaging, and Contemporary Treatment of Heart Valve Disorders provides a thorough and clinically focused exploration of the full spectrum of valve pathology, from fundamental anatomy and physiology to the latest innovations in structural heart intervention.

Beginning with the embryology, histology, biomechanics, and normal function of the cardiac valves, this text establishes a strong scientific foundation before guiding readers through the molecular mechanisms, hemodynamic consequences, and epidemiological patterns that drive valvular disease worldwide. Readers gain a deep understanding of rheumatic heart disease, degenerative and calcific valve disorders, infective endocarditis, congenital abnormalities, and other important etiologies that continue to shape global cardiovascular practice.

The book places particular emphasis on clinical excellence. Detailed chapters explore symptom assessment, physical examination, cardiac auscultation, peripheral signs, and diagnostic reasoning, helping clinicians integrate bedside findings with modern imaging technologies. Comprehensive coverage of transthoracic echocardiography, transesophageal echocardiography, three-dimensional imaging, Doppler quantification, cardiac CT, cardiac MRI, and multimodality imaging provides practical guidance for accurate diagnosis and procedural planning.

Major valvular disorders are examined in depth, including:

• Aortic stenosis and transcatheter aortic valve replacement (TAVR)

• Aortic regurgitation and contemporary intervention strategies

• Mitral stenosis and percutaneous balloon commissurotomy

• Primary and secondary mitral regurgitation

• Tricuspid valve disease and emerging transcatheter therapies

• Pulmonary valve disorders and right ventricular assessment

• Multi-valvular and combined valve disease

• Infective endocarditis and its structural complications

• Prosthetic heart valves and valve-in-valve procedures

Specialized chapters address valvular disease in pregnancy, elderly patients, athletes, congenital heart disease survivors, and individuals with systemic medical conditions. Readers are also introduced to multidisciplinary Heart Team decision-making, risk stratification frameworks, pharmacologic management, surveillance protocols, and the future of valve care, including next-generation transcatheter technologies, biological valve engineering, gene-based therapies, and digital health innovations.

Designed for cardiologists, cardiothoracic surgeons, cardiovascular fellows, internal medicine physicians, anesthesiologists, advanced practice providers, medical residents, and healthcare professionals involved in structural heart disease management, this volume combines scientific rigor with practical clinical application.

1. Foundations of cardiac valve anatomy, physiology, and biomechanics
2. Molecular and hemodynamic mechanisms of valvular disease
3. Advanced echocardiography, CT, MRI, and multimodality imaging
4. Evidence-based diagnosis and severity assessment
5. Surgical and transcatheter treatment strategies
6. Prosthetic valve management and valve-in-valve interventions
7. Infective endocarditis diagnosis and treatment
8. Heart Team decision-making and patient-centered care
9. Management of special populations and complex valve disorders
10. Emerging technologies shaping the future of structural heart disease

Combining foundational science, advanced diagnostics, and contemporary therapeutic approaches, Valvular Heart Disease serves as an authoritative guide for understanding, diagnosing, and managing one of the most important and rapidly advancing areas of cardiovascular medicine.