Type 1 Diabetes

The increasing incidence of diabetes worldwide has prompted a rapid growth in the pace of scientific discovery and clinical understanding of this enigmatic disease. In Type 1 Diabetes: Etiology and Treatment, well-recognized physicians and researchers review the latest thinking about the causes of this condition and the best approaches to treating both its acute and chronic complications. The treatment options discussed range from life-threatening diabetic ketoacidosis to contemporary insulin regimens, from open- and closed-loop insulin delivery devices to modern glucose-sensing mechanisms, as well as such daily life issues as nutrition and education. Also discussed are the management of children under the age of five, the special problems of preadolescents and adolescents, diabetic surgery, and pregnancy, along with the treatment and prevention of the long-term vascular complications that produce coronary artery disease, the loss of limbs, end-stage renal disease, and blindness. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets. Authoritative and up-to-date, Type 1 Diabetes: Etiology and Treatment provides all those caring for diabetic patients with a concise, accessible survey of today's best thinking about the causes, treatment, and management of this complex disease.