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The CRAC Channel

Language EnglishEnglish
Book Paperback
Book The CRAC Channel Bruno Constantin
Libristo code: 24510238
Publishers Springer New York, December 2019
This volume discusses the cellular and molecular techniques used to study and characterize the diffe... Full description
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This volume discusses the cellular and molecular techniques used to study and characterize the different components of the CRAC channel signaling pathway. The chapters in this book cover topics such as fluorescence-based measurements of the CRAC channel activity in cell populations; patch-clamp recording of the CRAC channel in STIM-Orai overexpressing cells and native systems; western-blotting and co-immunoprecipitation of endogenous STIM/ORAI and protein partners; shRNA-mediated gene silencing; and the SC-SMD system. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, The CRAC Channel: Methods and Protocols is a valuable resource for any researcher interested in learning more about the CRAC channel, as its activation mechanism and roles in cellular functions have yet to be completely explored.

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About the book

Full name The CRAC Channel
Author Bruno Constantin
Language English
Binding Book - Paperback
Date of issue 2019
Number of pages 204
EAN 9781493993703
ISBN 1493993704
Libristo code 24510238
Publishers Springer New York
Weight 419
Dimensions 178 x 15 x 12

Categories

Mathematics & Science > Biology, life sciences > Biochemistry
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