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Poly(ADP-Ribose) Polymerase

Name: Poly(ADP-Ribose) Polymerase
Brand: Springer, Berlin
SKU: 41459525
Price: 230.89 EUR
Availability: InStock
Author: Alexei V. Tulin
ISBN: 9781071628904

Methods and Protocols

Alexei V. Tulin

Language

English

Book Hardback

Libristo code: 41459525

Publishers Springer, Berlin, November 2021

This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and... Full description

Libristo code: 41459525

565 b

230.89 € VAT included

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This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway.