Phospholipases in Physiology and Pathology

Phospholipases in Physiology and Pathology is a thorough, comprehensive overview of the physiology and pathology of phospholipases. The 5-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Additionally, Phospholipases in Physiology and Pathology discusses the use of phospholipases and their metabolites, and the down-stream signaling components, as therapeutic targets for establishing prevention strategies. Volume 1 covers general aspects and signal transduction mechanisms. Volume 2 examines implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases. Volume 3 discusses implications in inflammation, apoptosis, gene expression and non-coding RNAs. Volume 4 explores the role of natural and synthetic compounds. Volume 5 examines stem cell therapies, nanotechnology-based therapies, bioinformatics and the system biology approach. Together these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives Features state-of-the-art chapter contributions from international leaders in the field