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The physiological processes involved in the absorption, distribution, metabolism, and excretion of xenobiotics and their corresponding pharmacological or toxicological responses in the body is studied through the integration of pharmacokinetics and toxicokinetics. By developing a firm understanding of this interrelation, appropriate approaches can be designed to achieve desirable outcomes. This book unifies important topics relevant to both disciplines through a logical and systematic approach, with emphasis on general principles and concepts rather than isolated observations. The author explores mathematical methodologies and