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Oxidant-Antioxidant Status
Mechanism of Action and Biochemical Parameters in Patients with Sickle Cell Disease
Language
English
English
Book
Paperback
It is inherited in an autosomal co dominant manner. Sickle cell disease is caused by point mutation...
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Libristo code: 16280118
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It is inherited in an autosomal co dominant manner. Sickle cell disease is caused by point mutation in the beta-Globin gene on chromosome 11, causing replacement of glutamic acid by valine at the sixth position of beta globin chain of Hb The altered amino acid content in beta-globin chain promotes the non-covalent polymerization (aggregation) of haemoglobin causing red blood cells to become sickle shaped and this decreases the elasticity of RBCs which is more pronounced during conditions of decreased oxygenation or higher oxygen demand as at higher altitude, infections, exercises and during surgery.
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About the book
Full name
Oxidant-Antioxidant Status
Author
Eman Refaat
Language
English
English
Binding
Book - Paperback
Date of issue
2017
Number of pages
88
EAN
9783330069572
Libristo code
16280118
Publishers
LAP Lambert Academic Publishing
Weight
149
Dimensions
150 x 220 x 5
Categories
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