Microglial Aging

Microglial Aging: Basic, Translational, and Clinical Advances covers the latest findings from basic, translational, and clinical research. The chapters review the physiological roles of microglia, the outcomes of aging on their structure and function, and their implication in age-related neurodegenerative diseases. Further, the book examines the effects of lifestyle that can potentiate beneficial microglial functions along the aging trajectory, thus preventing the onset of neurodegenerative diseases. Both pharmacological and non-pharmacological treatment strategies are discussed, including the ketogenic diet, cannabinoids, psychedelics, and non-invasive vagal nerve stimulation. With the demographically aging world population, increasing the quality of life and preventing age-related neurodegenerative diseases is currently of outmost importance. This book is a valuable resource for scientists and clinicians examining the impact of microglial health on aging.

• Covers basic, translational, as well as clinical research advances in microglial aging
• Reviews the most up-to-date research findings on microglial aging and their implication in age-related neurodegenerative diseases
• Includes current knowledge on the effects of the lifestyle on microglial aging and on the promising strategies, both pharmacological and non-pharmacological, for rejuvenating microglia