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Iron Chelation Therapy

Name: Iron Chelation Therapy
Brand: Springer Science+Business Media
SKU: 01379457
Price: 90.79 EUR
Availability: InStock
Author: Chaim Hershko
ISBN: 9780306467851

Chaim Hershko

Language

English

Book Hardback

Libristo code: 01379457

Publishers Springer Science+Business Media, January 2003

Within the last few years, iron research has yielded exciting new insights into the understanding of... Full description

Libristo code: 01379457

222 b

90.79 € VAT included

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Within the last few years, iron research has yielded exciting new insights into the understanding of normal iron homeostasis. Such development, and the evolution of improved strategies of Iron Chelating Therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant developments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload. This volume highlights the impact of long term Iron Celating Therapy using deferoxamine or the new, but controversial oral iron chelator deferiprone based on experience gained by multicenter trails, with special emphasis on survival, morbidity and drug toxicity; it reviews the development of the new and improved orally effective chelators suitable for clinical use in the near future and examines novel strategies of iron chelating treatment for the control of cell proliferation in malignant disease or malaria.