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Intradermal Immunization

Name: Intradermal Immunization
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 01658751
Price: 152.59 EUR
Availability: InStock
Author: Marcel B.M. Teunissen
ISBN: 9783642236891

Marcel B.M. Teunissen

Language

English

Book Hardback

Libristo code: 01658751

Publishers Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, September 2011

Despite the impressive success of current vaccine programs, there remains a need to improve the effe... Full description

Libristo code: 01658751

373 b

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Despite the impressive success of current vaccine programs, there remains a need to improve the effectiveness of current vaccines. A more powerful and longer lasting immune response induced by smaller and fewer doses of vaccine is an exciting challenge and necessary to reduce costs and to avoid vaccine shortages during pandemic epidemics. Improvement of effectiveness also enables induction of protective immunity in populations that respond poorly to vaccination, for example elderly or immunocompromised individuals. Furthermore, for some devastating infectious diseases (such as AIDS and malaria) effective vaccines have not been successfully developed. §The reviews in this volume of Current Topics in Microbiology and Immunology cover diverse topics related to intradermal immunization. The volume starts with a basic overview of murine and human skin dendritic cell network, respectively, and their role in immunity, as well as an extensive description of the immunobiology of the skin. The next chapter describes the state-of-the-art on delivery systems especially designed for intradermal vaccination. The remaining chapters highlight the effectiveness of intradermal immunization in experimental animal models or in clinical practice, all supporting the view that intradermal immunization is at least as good as other immunization routes.