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GLIPIZIDE EXTENDED RELEASE MATRIX TABLET

Name: GLIPIZIDE EXTENDED RELEASE MATRIX TABLET
Brand: LAP Lambert Academic Publishing
SKU: 07004980
Price: 45.79 EUR
Availability: InStock
Author: Ashish Mane
ISBN: 9783659234422

Design and In vitro Evaluation of Extended Release Glipizide Matrix Tablet

Ashish Mane

Ratnadeep Ghadage

Shitalkumar Patil

Language

English

Book Paperback

Libristo code: 07004980

Publishers LAP Lambert Academic Publishing, November 2011

The main goal of present study was formulation and in vitro evaluation extended release tablets of g... Full description

Libristo code: 07004980

112 b

45.79 € VAT included

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The main goal of present study was formulation and in vitro evaluation extended release tablets of glipizide.In this tablets glipizide was used as drug which is effective in management of diabetes for period of 12 hrs,which will increase patient compliance and be economical to the patient.Extended release tablets were prepared using polymer HPMC K4M, HPMC K15M, HPMC K100M with suitable excipients.Tablets showed initial release to initiate pharmacological action and slowing releasing drug to maintain therapeutic action.Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, swelling property, drug content uniformity and dissolution study.Disintegration time and drug release were taken as basis to optimise the tablets.Accelerated stability study for optimised batch was also performed.