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This book discusses genome engineering using the protein CRISPR-Cas9. The bulk of chapters are devoted to site- or disease-specific genome editing including for immune function, diabetes, cancer stem cell reprogramming, retinal disease and cardiovascular disease. Final chapters on current controversies and future directions round out the discussion. Covering the state-of-the-science on this rapidly developing topic, this book will be essential reading for all clinicians and researchers in stem cells or regenerative medicine, genomics or biochemical/biomedical engineering, interested in learning more about genome editing and applying it in a targeted, specific way.
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