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Gene Essentiality

Methods and Protocols

Language EnglishEnglish
Book Paperback
Book Gene Essentiality Long Jason Lu
Libristo code: 15178621
Publishers Humana Press Inc., October 2016
This volume opens by covering two main types of approaches widely used to determine essential genes:... Full description
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This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans . Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Gene Essentiality: Methods and Protocols will aid researchers who wish to further our knowledge in this vital field of study.

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About the book

Full name Gene Essentiality
Author Long Jason Lu
Language English
Binding Book - Paperback
Date of issue 2016
Number of pages 248
EAN 9781493948628
ISBN 1493948628
Libristo code 15178621
Publishers Humana Press Inc.
Weight 5533
Dimensions 178 x 254 x 14
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