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Gaschromatographie

Eine anwenderorientierte Darstellung

Language GermanGerman
Book Paperback
Book Gaschromatographie Peter J. Baugh
Libristo code: 06950401
Publishers Springer, Berlin, November 2011
c) Speichel a) Plasma b) Urin 4 4 4 3 3 2 2 1 1 3 1 2 L ~ I I I I I 8 0 4 8 8 Zeit (min) Bild 6. 7 G... Full description
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c) Speichel a) Plasma b) Urin 4 4 4 3 3 2 2 1 1 3 1 2 L ~ I I I I I 8 0 4 8 8 Zeit (min) Bild 6. 7 Gaschromatogramme von Nikotin und Cotinin in Plasma, Urin und Speichel: Trennsaule: HP-FFAP, 7 m x 0,32 mm ID, 0,52 Ilm Film; Temperaturprogramm: 70°C, 40 a/min bis 115°C, 1,5 min isotherm, 40 a/min bis 200 °C, 2,25 min isotherm, 40 a/min bis 210 °C, 2,75 min isotherm, Analysenzeit: 10 min; Tragergas: Helium (Saulenvordruck 105 kPa); Detektor: NPD; Extraktion: s. Protokoll 6. 3; Injektion: 2 III Extrakt; Konzentrationen von Nikotin und Cotinin: a) im Plasma 23 und 27Ilg/l, b) im Urin 73 und 100 Ilg/l, c) im Spei chel 115 und 130 Ilg/l; Peaks: I -Nikotin, 2 -Cotinin, 3 -3-Methylcotinin (interner Standard), 4 -Coffein. (Nachdruck aus Ref. [13]) 6. 3. 4. 5 Nikotin Nikotin als Bestandteil des Tabaks reicht nicht aus, urn akute Vergiftungen auslOsen zu kon nen, es sei denn, Tabak wird von kleinen Kindem aufgenomrnen. Allerdings ist Nikotin in einigen pflanzlichen Medikamenten in haherer Dosis enthalten und wird zum Teil auch im Gartenbau zum Ausrauchem von Schadlingen verwendet. 1m Karper wird es durch N-Derne thylierung zu Cotinin metabolisiert. Neben der Moglichkeit akuter Nikotinvergiftungen sind vor allem Studien zum Rauchverhalten haufig der Grund fUr eine Bestimmung von Nikotin undloder Cotinin in biologischen Proben.

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About the book

Full name Gaschromatographie
Language German
Binding Book - Paperback
Date of issue 2012
Number of pages 426
EAN 9783642638626
ISBN 3642638627
Libristo code 06950401
Publishers Springer, Berlin
Weight 760
Dimensions 170 x 244 x 23
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