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Crystals, X-rays and Proteins

Language EnglishEnglish
Book Paperback
Book Crystals, X-rays and Proteins Jon Cooper
Libristo code: 04528530
Publishers Oxford University Press, March 2015
A complete account of the theory of the diffraction of X-rays by crystals, with particular reference... Full description
? points 213 b
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A complete account of the theory of the diffraction of X-rays by crystals, with particular reference to the processes of determining the structures of protein molecules. This book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including: - The practical aspects of sample preparation and X-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels - The important role played by the Patterson function in structure analysis, by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods: these reveal further detail of great functional importance in a crystal structure.

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About the book

Full name Crystals, X-rays and Proteins
Language English
Binding Book - Paperback
Date of issue 2015
Number of pages 644
EAN 9780198726326
ISBN 0198726325
Libristo code 04528530
Weight 1272
Dimensions 173 x 247 x 31
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