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Cardiac Extracellular Matrix

Name: Cardiac Extracellular Matrix
Brand: Springer International Publishing AG
SKU: 19745290
Price: 171.49 EUR
Availability: InStock
Author: Eric Schmuck
ISBN: 9783319974200

Fundamental Science to Clinical Applications

Eric Schmuck

Peiman Hematti

Amish N. Raval

Language

English

Book Hardback

Libristo code: 19745290

Publishers Springer International Publishing AG, October 2018

This book features three sections, Fundamental Science, Pre-Clinical and Translational Science, and... Full description

Libristo code: 19745290

420 b

171.49 € VAT included

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This book features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM's role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.