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Biodegradable Microspheres

Delivery of Mirtazapine through biodegradable microspheres

Language EnglishEnglish
Book Paperback
Book Biodegradable Microspheres Vivek Dave
Libristo code: 06838376
Publishers VDM Verlag, November 2010
The aim of this study was to develop a depot formulation of mirtazapine by w/o emulsification method... Full description
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The aim of this study was to develop a depot formulation of mirtazapine by w/o emulsification method using chitosan as controlled release biodegradable polymer. Chitosan microspheres are used to provide controlled release of mirtazapine and to improve the bioavailability of degradable substances or enhance the uptake of hydrophilic substances across the epithelial layers. The effect of various parameters, such as stirring rate, drug to chitosan ratio, chitosan concentration and glutaraldehyde concentration on entrapment efficiency and release study was studied. Stirring speed affects the size of microspheres, drug to chitosan ratio and chitosan concentration affects the entrapment efficiency and release study; glutaraldehyde concentration affects the release of the drug molecule from the microspheres.

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About the book

Full name Biodegradable Microspheres
Language English
Binding Book - Paperback
Date of issue 2010
Number of pages 88
EAN 9783639315066
ISBN 3639315065
Libristo code 06838376
Publishers VDM Verlag
Weight 141
Dimensions 152 x 229 x 5
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