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Advancing Methods for Biomolecular Crystallography

Name: Advancing Methods for Biomolecular Crystallography
Brand: Springer
SKU: 01980530
Price: 214.29 EUR
Availability: InStock
Author: Randy Read
ISBN: 9789400763197

Randy Read

Alexandre G. Urzhumtsev

Vladimir Y. Lunin

Language

English

Book Paperback

Libristo code: 01980530

Publishers Springer, April 2013

This work presents a snapshot of the state of the art of modern biomolecular crystallography, from c... Full description

Libristo code: 01980530

524 b

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This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.