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Activity-Based Protein Profiling

Design and synthesis of activity-based probes (ABPs), adaptation of activity-based protein profiling (ABPP) for plant proteomes studies

Language EnglishEnglish
Book Paperback
Book Activity-Based Protein Profiling Zhe-Ming Wang
Libristo code: 06830493
Publishers VDM Verlag Dr. Müller, November 2009
Until now, the only technology to directly demonstrate the role of switching between the active/inac... Full description
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Until now, the only technology to directly demonstrate the role of switching between the active/inactive states of enzymes during plant defence is ABPP. Since the discovery of ABPP ten years ago, several ABPs have been developed and used in pharmacological and physiological studies. However, a broader use of ABPP is still limited by the availability of suitable probes. In an attempt to expand this limited applicability of ABPP, in this thesis, new types of ABPs were designed, synthesized and evaluated as potential probes for the study of plant-pathogen interactions. To develop effective ABPs in an efficient way, different design strategies have been tested and discussed accompanying with five questions, to generate different types of novel ABPs ...

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About the book

Full name Activity-Based Protein Profiling
Author Zhe-Ming Wang
Language English
Binding Book - Paperback
Date of issue 2010
Number of pages 304
EAN 9783639227086
Libristo code 06830493
Weight 469
Dimensions 150 x 220 x 18
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